Figure 6
DNA ladder assay for detection of DNA damages in MCF-7 cells. Lanes A, B, C and D respectively represent the untreated control cells, the treated cells with the free MNPs (10.71 μg/mL), the PEGylated FA-MTX-MNPs (12.31 μg/mL), or the free MTX (1.60 μg/mL) treated cells for 48 h. M: Marker (100 base-pair). FA: folic acid. MTX: mitoxantrone. MNPs: magnetic nanoparticles.