Figure 9From: Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells FITC-conjugated annexin V apoptosis analysis of MCF-7 cells. A) The untreated cells (negative control). B) The cells treated with the free MNPs (10.71 μg/mL). C) The cells treated with the free MTX (1.60 μg/mL). D) The cells treated with the PEGylated FA-MTX-MNPs (12.31 μg/mL). FITC: Fluorescein isothiocyanate. FA: folic acid. MTX: mitoxantrone. MNPs: magnetic nanoparticles.Back to article page