Table 2 Results of NLC formulation optimization experiment using a U*7(74) uniform experimental design (mean ± standard deviation, n = 3)
NLCs | Response (Y1) | Response (Y2) | Response (Y3) | Response (Y4) | Response (Y5) |
|---|---|---|---|---|---|
Size (nm) | EE (LA, %) | EE (RAN, %) | DL (LA, %) | DL (RAN, %) | |
NLC1 | 374.0 ± 25.7 | 54.70 ± 7.23 | 48.93 ± 5.63 | 0.78 ± 0.05 | 0.04 ± 0.01 |
NLC2 | 137.2 ± 11.3 | 66.82 ± 2.66 | 57.78 ± 1.97 | 1.33 ± 0.12 | 0.02 ± 0.01 |
NLC3 | 353.4 ± 28.5 | 66.07 ± 8.63 | 65.27 ± 9.73 | 2.14 ± 0.11 | 0.12 ± 0.02 |
NLC4 | 508.7 ± 68.7 | 81.45 ± 5.92 | 57.46 ± 3.24 | 6.67 ± 0.58 | 0.26 ± 0.02 |
NLC5 | 424.3 ± 41.2 | 88.25 ± 7.22 | 80.84 ± 8.45 | 8.89 ± 0.57 | 0.85 ± 0.02 |
NLC6 | 157.9 ± 20.3 | 93.14 ± 6.12 | 83.86 ± 7.23 | 13.58 ± 1.21 | 1.59 ± 0.09 |
NLC7 | 97.1 ± 11.2 | 71.31 ± 4.32 | 78.85 ± 6.11 | 1.91 ± 0.22 | 0.21 ± 0.02 |