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Table 3 Antimicrobial and hemolytical activities of PMMA/PDDA NPs

From: The antimicrobial activity of free and immobilized poly (diallyldimethylammonium) chloride in nanoparticles of poly (methylmethacrylate)

Dispersion

MMC (% H)

E. coli

S. aureus

C. albicans

PDDA

0.005 (0)

>0.5 (0)

0.005 (0)a

A3

0.007 (0)

0.1 (15)

>0.8 (>63)

A4

0.007 (0)

0.5 (20)

>0.8 (>33)

A5

0.007 (0)

0.5 (48)

>1.0 (>75)

B3

0.010 (0)

0.6 (23)

>1.0 (>41)

B4

0.003 (0)

0.8 (65)

>1.5 (>90)

B5

0.003 (0)

0.8 (48)

>1.5 (>83)

  1. MMC, in mg mL−1, and hemolysis percentiles in between parentheses (% H) at the MMC for free PDDA or in the PDDA/PMMA NPs
  2. aFor PDDA against C. albicans, MMC is the smallest [PDDA] leading to a five-log reduction of cell viability