The antimicrobial activity of free and immobilized poly (diallyldimethylammonium) chloride in nanoparticles of poly (methylmethacrylate)

Table 4 The dependence of antimicrobial activity on the microorganism, M_w and hydrophobic–hydrophilic balance of the cationic polymer

Microorganism	MMC (µg/mL)					References
	PDAATFA		PDAMATFA, M_w (kDa)		PDDA
	24	62	24	55	150
E. coli ATCC 25922	125 ± 7.5^a	15 ± 1.8^a	62 ± 5.0^a	7 ± 1.0^a		[39]
E. coli ATCC 25922					5	This work
P. aeruginosa ATCC 9027		125 ± 7.5^a		31 ± 3.1^a		[39]
P. aeruginosa MDR					1.5^b	[35]
K. pneumoniae ATCC 13883		15 ± 1.8^a		62 ± 5.0^a		[39]
K. pneumoniae KPC+					0.9^b	[35]
S. aureus ATCC 6538 P	31 ± 3.1^a	1.5 ± 0.3^a	62 ± 5.0^a	7 ± 1.0^a		[39]
S. aureus ATCC 29213					>500^b	This work
MRSA					5.0^b	[35]
C. albicans ATCC 865-653	3.5 ± 0.6^a	1.5 ± 0.3^a	3.5 ± 0.3^a	3.5 ± 0.6^a		[39]
C. albicans ATCC 90028					5	This work
C. albicans fluconazole resistant					0.8^b	[35]

MMC, in mg mL⁻¹, for PDAATFA, PDAMATFA and PDDA against bacteria and fungi. The M_w value is given in kDa. The hydrophobic–hydrophilic balance increases with methylation of the nitrogen. PDAATFA, PDAMATFA and PDDA have none, one or two methyl groups attached to the nitrogen, respectively
^aThe MMC is the minimal concentration for the total inhibition of microorganism growth
^bThe minimal concentration for reduction of CFU counting to one

ISSN: 1477-3155