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Table 2 The AgNP concentrations necessary to induce cell death at the given survival level

From: Glucose availability determines silver nanoparticles toxicity in HepG2

Dead cells %

AgNP concentrations necessary to induce cell death at the given survival level (µg/cm3)

High glucose culture

Low glucose culture (24 h)

Low glucose culture (30 days)

10b

1.81 ± 0.41

2.52 ± 0.57

13.84 ± 2.05

25b

4.60 ± 0.58

5.82 ± 0.73

22.91 ± 1.93

50b

11.70 ± 0.93

13.45 ± 1.15

37.94 ± 7.63

75a

29.75 ± 4.46

31.06 ± 4.99

62.83 ± 22.235

90a

75,61 ± 19.35

71.77 ± 19.33

104 ± 21.63

  1. Values of each IC were compared by ANOVA accompanied by Tukey’s post test
  2. Values represent means ± half of respective confidence intrerval, α = 0.05, n = 3
  3. aDenotes statistically important difference between low glucose (30 days) and other cultures
  4. bMeans that viability of each culture differs from other two