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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Rough surface Au@Ag core–shell nanoparticles to fabricating high sensitivity SERS immunochromatographic sensors

Fig. 2

a Schematic diagram of the SERS ICSs for detecting haemoglobin. The SERS ICSs consists of five overlapping layers: absorption pad, NC membrane, conjugation pad and sample pad, which were placed on a plastic backing. Capture mAb was dispensed at T-line. When the SERS ICSs detected negative samples, Raman signal at T-line was weak; whereas, when the SERS ICSs detected positive samples, Raman signal at T-line was strong. b Concentration dependent SERS spectra of SERS ICSs obtained from detecting different concentrations of haemoglobin: The entire SERS spectra are shown in Additional file 1: Figure S10–21. Detailed vibrational assignments of Raman peaks are presented in Additional file 1: Table S1. c Calibration curve of SERS ICSs for the detection of haemoglobin

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