Fig. 2From: Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum componentsTEM micrographs of AuNP endocytosis and intracellular trafficking by THP-1 cells. Images show 6 h incubation with a medium only, b Au_SC, c Au_CHIT-L, d Au_CHIT-H; and Au_CHIT-H-containing vesicles shown fusing at the cell surface and eventual exocytosis (e, f); AuNPs compartmentalised within endocytotic vesicles identified by black arrows; with nucleus, mitochondria and extracellular space identified by N, M and X, respectivelyBack to article page