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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Engineered atherosclerosis-specific zinc ferrite nanocomplex-based MRI contrast agents

Fig. 2

Enhancement in MRI/CT contrast and internalisation efficacy of nanoparticles. a Slight enhancement of T1 MRI contrast was observed in Hsp-70 Lf-PEG-ZF compared to ferrite nanoparticles. b Significant enhancement of T2 MRI contrast was observed in Hsp-70 Lf-PEG-ZF compared to ferrite nanoparticles. c Slight enhancement of CT contrast was observed in Hsp-70 Lf-PEG-ZF compared to ferrite nanoparticles. d Confocal microscopy internalization images and cell cytometric internalization assessment displaying time-dependent internalization of Hsp-70 Lf-ZF, Hsp-70 Ch-Lf-ZF and Hsp-70 Lf-PEG-ZF nanocomplexes in THP-1 cells and e Jurkat cells. Effective internalization was observed at 2 h Hsp-70 Lf-ZF nanocomplex post-treatment

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