Skip to main content

Table 2 The main assessment criteria for histological skin lesions

From: Anti-inflammatory effect of fullerene C60 in a mice model of atopic dermatitis

No.

Criterion

The degree of manifestation

Score

1

Epidermal thickening

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

2

Epidermal necrosis

Absent

0

  

Present

1

3

Epidermal hyperkeratosis

Absent

0

  

Present

1

4

Connective tissue like dermal proliferation

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

5

Dermal necrosis

Absent

0

  

Present

1

6

Dermal swelling

Absent

0

  

Present

1

7

Dermal hemorrhage

Absent

0

  

Present

1

8

Connective tissue like subcutaneous fat proliferation

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

9

Subcutaneous fat necrosis

Absent

0

  

Present

1

10

Subcutaneous fat swelling

Absent

0

  

Present

1

11

Subcutaneous fat hemorrhage

Absent

0

  

Present

1

12

Cell infiltration of dermis

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

13

Cell infiltration of dermis (eosinophils)

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

14

Cell infiltration of dermis (polynuclear leukocytes)

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

15

Cell infiltration of dermis (lymphocytes)

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

16

Cell infiltration of subcutaneous fat

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

17

Cell infiltration of subcutaneous fat (eosinophils)

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

18

Cell (polynuclear leukocytes) infiltration of subcutaneous fat

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3

19

Cell (lymphocytes) infiltration of subcutaneous fat

Absent

0

  

Mild

1

  

Moderate

2

  

Pronounced

3