Fig. 1
From: Inhibition of breast cancer with transdermal tamoxifen-encapsulated lipoplex
The characteristics of LPPC/TAM. TAM encapsulated in 10 mg of LPPC at various weight ratios. The (a) particle size, (b) zeta-potential and (c) TAM encapsulation of LPPC/TAM were measured. *p < 0.05 or ** p < 0.01, compared with the LPPC group. d TAM release from LPPC/TAM in PBS at 4, 25 and 37 °C. *p < 0.05, 37 °C group was compared with the 4 °C group; # p < 0.05, 25 °C group was compared with the 4 °C group. e TAM release from LPPC/TAM in PBS with pH 6.0, 7.4 or 8.0 at 37 °C. After the incubation, the percentage of TAM in each supernatant was measured and compared with the total amount of TAM (n = 6)