Fig. 7

Internalization of graphene oxide-silver nanocomposite by J774 tumoral macrophages. a Macrophage in low magnification (6000×). b Detail of vacuole containing the internalized nanocomposite. c Highlight of the nanocomposite inside the vacuole with black arrowheads pointing to silver nanoparticles on graphene oxide sheets. d, e, and f amplified images of the nanocomposite inside cell vacuoles. The black arrowheads indicate silver nanoparticles on graphene oxide sheets. g High-magnification of cell compartments containing degraded GOAg nanocomposite (47,000×). h Detail of the cell compartment containing degraded GOAg nanocomposite and close to a vacuole. i Detail of a partially degraded GOAg sheet and close to the border of a vacuole