Comparative in vitro toxicity of a graphene oxide-silver nanocomposite and the pristine counterparts toward macrophages

Table 2 Summary of the toxicity of graphene-silver nanocomposite and its counterparts toward macrophages

Nanomaterial (µg mL⁻¹)	IC_50–24 h	CI 95 %	IC_50–48 h	CI 95 %
MØ J774
GO	16.9	(10.1–28.2)	58.4	(42.4–80.5)
AgNP	8.9	(7.0–11.3)	2.9	(1.8–4.6)
GOAg	2.9	ND	3.8	ND
MØ peritoneal
GO	32.9	ND	24.7	ND
AgNP	10.4	(7.2–14.9)	3.0	(2.4–3.75)
GOAg	3.1	(2.5–3.8)	2.9	(2.0–4.2)

IC50 50 % inhibitory concentration, CI 95 % confidence interval, MØ macrophage, ND not determined. The IC50 and CI are expressed in µg mL⁻¹

ISSN: 1477-3155