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Fig. 8 | Journal of Nanobiotechnology

Fig. 8

From: Iron oxide nanoparticles for neuronal cell applications: uptake study and magnetic manipulations

Fig. 8

a Phase contrast images of leech neurons in culture in the presence of a magnetic field, either with MNPs or without (control). The neurites were traced and the direction of their tips was measured by calculating their angle relative to the direction of the magnetic field (inset). b Analysis of the direction of neurites outgrowth in the absence (control) or in the presence of MNPs, under an external magnetic field. The resultant vector length (marked in red) in the control group is 0.074 and the resultant vector length in the experiment group is 0.386 (p = 0.116, n = 312 and p = 0.009, n = 29, respectively, according to Rayleigh test for uniformity)

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