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Table 2 Average and median values of NP uptake in single Neuro-2a cells

From: Quantification and visualization of cellular uptake of TiO2 and Ag nanoparticles: comparison of different ICP-MS techniques

Sample/unit

Median

Average ± SD

50 nm Ag (pg per cell)

72

81 ± 67

50 nm Ag (NPs per cell)

126,085

142,394 ± 117,729

75 nm Ag (pg per cell)

164

205 ± 188

75 nm Ag (NPs per cell)

73,684

92,152 ± 84,502

7 nm TiO2 (integrated signal intensity cps per cell)

107,242

136,234 ± 103,648

7 nm TiO2 (relative NPs per cell)

4.8 × 1011

6.0 × 1011 ± 4.6 × 1011

20 nm TiO2 (integrated signal intensity cps per cell)

281,341

310,732 ± 203,387

20 nm TiO2 (relative NPs per cell)

6.3 × 1010

6.9 × 1010 ± 4.6 × 1010

  1. The cellular uptake was analyzed by LA-ICP-MS. Exposure concentration: 2 µg/mL