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Table 2 rGO effects on hematological parameters of male Wistar rats

From: Reduced graphene oxide: nanotoxicological profile in rats

Group Unit Control rGO 15 min rGO 1 h rGO 3 h rGO 7 days
RBC 106/μl 7.32 ± 0.09 7.16 ± 0.17 7.45 ± 0.02 7.27 ± 0.11 7.48 ± 0.04
Hb g/dl 14.27 ± 0.24 13.73 ± 0.12 14.37 ± 0.14 14.00 ± 0.24 14.32 ± 0.37
Hct % 46.87 ± 0.52 46.13 ± 0.88 48.83 ± 0.57 47.58 ± 0.24 47.70 ± 0.40
MCV fl 64.00 ± 0.60 64.60 ± 0.23 65.53 ± 1.02 65.44 ± 0.66 63.44 ± 0.49
MCH pg 19.03 ± 0.23 19.03 ± 0.32 19.27 ± 0.24 19.22 ± 0.21 19.24 ± 0.26
MCHC g/dl 29.80 ± 0.40 29.57 ± 0.40 29.43 ± 0.08 29.42 ± 0.42 30.38 ± 0.33
PLT 103/μl 638.3 ± 5.84 650.0 ± 6.92 649.0 ± 10.69 624.2 ± 25.81 636.2 ± 59.19
WBC 103/μl 7.63 ± 0.60 6.80 ± 1.41* 7.10 ± 0.30 10.83 ± 0.55*,# 5.03 ± 0.56#
  1. The same symbol in each column indicates a significant difference between groups
  2. One-way ANOVA, Bonferroni post hoc test; data were shown as mean ± SEM, n = 3–5 in each group
  3. RBC red blood cell; Hb hemoglobin; Hct hematocrit; MCV mean corpuscular volume; MCH mean corpuscular hemoglobin; MCHC mean corpuscular hemoglobin concentration; PLT platelet; WBC white blood cell
  4. *p < 0.05; #p < 0.01