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Table 3 Effects of rGO on biochemical parameters of hepatic and renal function

From: Reduced graphene oxide: nanotoxicological profile in rats

  Unit Control rGO 15 min rGO 1 h rGO 3 h rGO 7 days
ALT U/L 44 ± 3.5 56 ± 3.9 54 ± 0.5 44 ± 3.2 48 ± 2.3
AST U/L 148 ± 9.9 177 ± 8.4 152 ± 7.5 156 ± 9.5 151 ± 6.6
BUN mg/dL 48 ± 2.2# 57 ± 3.2*, 45 ± 3.3* 35 ± 0.7#, 48 ± 1.8
Creatinine mg/dL 0.31 ± 0.003 0.35 ± 0.017 0.29 ± 0.021 0.30 ± 0.017 0.34 ± 0.020
  1. Values are mean ± SEM of 3–5 animals in each group. The same symbol in each column indicates a significant difference between groups
  2. One-way ANOVA, Bonferroni post hoc test
  3. ALT alanine aminotransferase; AST aspartate aminotransferase; BUN blood urea nitrogen
  4. #,* p < 0.05; p < 0.001