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Table 5 Effect of rGO on the frequency of polychromatic erythrocytes with micronuclei in the peripheral blood and caspase-3 expression

From: Reduced graphene oxide: nanotoxicological profile in rats

 

Control

rGO 15 min

rGO 1 h

rGO 3 h

rGO 7 days

Micronucleus index

0.68 ± 0.13

NA

NA

NA

0.64 ± 0.19

Caspase 3

92.46 ± 2.88

101.3 ± 11.66

91.71 ± 8.00

89.05 ± 15.99

95.97 ± 14.46

  1. Protein expression levels were expressed as percentage of control (100 %) after normalization to an internal standard (β-actin). One-way ANOVA, Bonferroni post hoc test; data were shown as mean ± SEM; n = 5 in each group
  2. NA not assessed