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Table 5 Effect of rGO on the frequency of polychromatic erythrocytes with micronuclei in the peripheral blood and caspase-3 expression

From: Reduced graphene oxide: nanotoxicological profile in rats

  Control rGO 15 min rGO 1 h rGO 3 h rGO 7 days
Micronucleus index 0.68 ± 0.13 NA NA NA 0.64 ± 0.19
Caspase 3 92.46 ± 2.88 101.3 ± 11.66 91.71 ± 8.00 89.05 ± 15.99 95.97 ± 14.46
  1. Protein expression levels were expressed as percentage of control (100 %) after normalization to an internal standard (β-actin). One-way ANOVA, Bonferroni post hoc test; data were shown as mean ± SEM; n = 5 in each group
  2. NA not assessed