Fig. 7

In vivo pharmacokinetics of EF24 loaded liposomes. a Graphical representation of the results from LC–MS/MS measurements. Left linear scale; right semilogarithmic scale. Plasma concentrations of EF24 were determined at 0.25, 1, 2, 3, 4, 6, 8 and 24 h after intravenous administration of liposomal EF24 formulation, given as single dose equivalent to 10 mg/kg EF24. For each time point data from at least two to four mice were analysed. b Graphical representation of the results of free (not encapsulated) EF24 solubilized in DMSO from LC–MS/MS measurements. Left linear scale; right semilogarithmic scale