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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Impact of degradable nanowires on long-term brain tissue responses

Fig. 2

Inflammatory tissue response, cell nuclei and neuronal density (outer ROI). Quantification in the outer ROI (50–150 μm) of ED1-positive area (a), GFAP-positive area (b), NeuN density (c), and cell nuclei density (d) at 1 year for HfOx-coated GaP nanowires (biostable) and SiOx-coated GaP nanowires in vehicle solution (biostable). The boxes correspond to median values with indication of the 25 and 75 percentiles, and the whiskers show the minimum and maximum values. Mann–Whitney test was used. Representative fluorescent images of the tissue response 1 year post injection of e 2 μm long HfOx-coated nanowires (biostable) and f 2 µm long SiOx-coated GaP nanowires (degradable). Neuronal nuclei (green), GFAP-positive cells (red) and cell nuclei (blue). Scale bar 100 μm

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