Table 1 Different types of transgenic zebrafish used to the nanoparticle/chemical toxicity study
From: Zebrafish: A complete animal model to enumerate the nanoparticle toxicity
| Â | Nanoparticle/chemicals used | Transgenic zebrafish type that is used to understand the nanoparticle toxicity | Remark | References |
|---|---|---|---|---|
1. | TiO2, SiO2, CuO | Transgenic (nacre/fli1:EGFP) zebrafish | Transgenic fish exposed to TiO2,SiO2, CuO particles with a concentration of 0.01, 1 and 100 μg/ml concentrations and noted that CuO nanoparticles inhibit vasculogenesis | [140] |
2. | TiO2, C60(OH)24) (hydroxylated fullerenes/) | Gene expression of zebrafish embryos | Circadian rhythm gene/(s) deregulated by nanoparticles | [141] |
3. | TiO(2) | ARE transgenic zebrafish | Exposure TiO(2) nanoparticle cause death of zebrafish embryos | [137] |
4. | Small molecules | Transgenic embryos expressing green fluorescent protein in myocardium | Small molecule alter in heart rate of transgenic embryos | [142] |
5. | Metal oxide nanoparticles such as CuO, ZnO, NiO, and Co(3)O(4)) | hsp70:eGFP transgenic zebrafish larvae | CuO, ZnO, and NiO may augmented expression of hsp70:eGFP in transgenic zebrafish larvae | [136] |
6. | Inorganic nanorods | Transgenic (fli1a:EGFP) zebrafish embryos | This study noted that—ROS mediated angiogenesis in transgenic zebrafish embryo using inorganic nanorods | [143] |
7. | Cadmium selenium (CdSe) quantum dots (QDs) coated with mercaptopropionic acid (MPA) | FLI-1 transgenic zebrafish larvae | abnormal vascularization occoured in transgenic zebrafish larvae | [144] |
8 | Mesoporous silica nanoparticles (MSNPs) | lysC:DsRED2 transgenic embryos | It can be used to deliver bioactive compounds | [145] |