Fig. 1From: High efficiency penetration of antibody-immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cellsThe penetration of nanoneedle through cellular membrane. a Scanning ion microscopy (SIM) image of an AFM cantilever type nanoneedle which was obtained immediately after the fabrication by FIB. The nanoneedle was approached to adhering cell to penetrate plasma membrane. b Side views reconstructed from confocal fluorescence images of CLSM are showing the successful penetration. c Side views reconstructed from confocal fluorescence images of CLSM are showing the failed caseBack to article page