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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Targeted drug delivery of near IR fluorescent doxorubicin-conjugated poly(ethylene glycol) bisphosphonate nanoparticles for diagnosis and therapy of primary and metastatic bone cancer in a mouse model

Fig. 4

Targeting ability of Cy7-cojugated BP NPs compared to control NPs. Histogram of the difference in fluorescence between day 1 and day 7 of each NP. The fluorescence of the BP NPs remains constant indicating that they are retained in the area of the tumor, whereas the fluorescence of the control NPs is reduced, indicating that they have been cleared from the tumor area (analyzed by ImageJ software). Error bars represent standard deviation

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