Fig. 3From: Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer a–d Nanoparticle synthesis: a synthetic route to t-PA decoration of both CAN-Mag-Chitosan and CAN-Mag-Chitosan-PEG NPs. TEM microphotographs of t-PA-decorated (b) CAN-Mag-Chitosan and (c) CAN-Mag-Chitosan-PEG NPs. d Schematic presentation of the preparation of the final nanosystem CAN-Mag@PNPs-PEG-REGAcp-PEG/tPA-pep1Lac Back to article page