Skip to main content
Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer

Fig. 5

MRI: a minor portion of the injected NPs reach the tumor. Axial presentation of subcutaneous (sc) and orthotopic (ot) Panc-1 tumors T2-weighted images of a single slice before (left) and 5 min after injection (right) of CAN-Mag@PNPs (top); CAN-Mag@PNPs-tPApep1Lac (middle); and CAN-Mag@PNPs-PEG-REGAcp-PEG/tPA-pep1Lac NPs injection (bottom). The circled tumor areas represents the regions of interest (ROI) used for the analysis of signal intensity loss. The dashed circle areas are the muscle areas used as reference ROI. A signal drop (darker area) in the s.c. and ot. tumors can be seen after NP application in the T2 weighted images

Back to article page

Journal of Nanobiotechnology

ISSN: 1477-3155

Contact us