Fig. 6From: Hyaluronic acid-coated chitosan nanoparticles induce ROS-mediated tumor cell apoptosis and enhance antitumor efficiency by targeted drug delivery via CD44Cell apoptosis determined by Annexin V–fluorescein isothiocyanate/propidium iodide staining. The results were determined after incubation with free 5-Fu, 5-Fu-loaded CS NPs, 5-Fu-loaded HA-coated CS NPs, free HA and 5-Fu-loaded HA-coated CS NPs, and 5-Fu-loaded HA-coated CS NPs combined with NAC for 24 h (n = 3)Back to article page