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Fig. 7 | Journal of Nanobiotechnology

Fig. 7

From: Enhancement of scutellarin oral delivery efficacy by vitamin B12-modified amphiphilic chitosan derivatives to treat type II diabetes induced-retinopathy

Fig. 7

The effect of Scu, Chit-DC-Scu and Chit-DC-VB12-Scu on blood flow rate and pathological structure of the diabetic retina. a Color Doppler sonography analysis was performed in the retina of experimental rats. Quantitative evaluation of retinal blood flow velocity (b) and RI (c) of rats in each group. d The pathological changes in the retina of rats observed under the microscope with Hematoxylin–eosin staining (×200). The arrangement of ganglion cells and inner nuclear layer cells was disorder in T2D rats groups (indicated by the black arrow). *Significantly different from control group (P < 0.05); #significantly different from DM group (P < 0.05)

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