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Table 1 Ultrasound parameters of targeted and blank nanobubbles in liver, kidney and transplanted tumors

From: Construction of ultrasonic nanobubbles carrying CAIX polypeptides to target carcinoma cells derived from various organs

Tissue

Contrast agent

Peak time/s

Peak intensity/dB

Duration time/min

Liver

TN

6.22 ± 0.50

18.31 ± 0.61

21.46 ± 0.87

BN

6.32 ± 0.95

18.52 ± 0.95

21.19 ± 1.68

Kidney

TN

2.01 ± 0.34

17.48 ± 0.76

20.11 ± 1.20

BN

2.37 ± 0.59

17.42 ± 0.87

19.77 ± 0.77

786-O tumor

TN

8.28 ± 0.74

21.56 ± 0.62*,#

21.35 ± 0.51*,#

BN

8.44 ± 0.71

19.30 ± 0.68

17.91 ± 0.81

Hela tumor

TN

8.31 ± 0.75

20.51 ± 0.69*,#

20.93 ± 0.61*,#

BN

8.25 ± 0.78

18.53 ± 0.42

17.99 ± 0.85

BxPC-3 tumor

TN

8.04 ± 0.85

18.34 ± 0.65

17.55 ± 0.53

BN

8.41 ± 0.43

18.53 ± 0.60

17.66 ± 0.84

  1. * Compared with the same indicator from blank nanobubbles, P < 0.05
  2. #Compared with the same indicator from BxPC-3 transplanted tumor tissues, P < 0.05