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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Identification of epidermal growth factor receptor-positive glioblastoma using lipid-encapsulated targeted superparamagnetic iron oxide nanoparticles in vitro

Fig. 3

Schematic of anti-EGFR antibody cetuximab conjugated to lipid-encapsulated nonfouling SPIO nanoparticles. Maghemite nanoparticles were modified with maleimide through reaction with sulfo-SMCC; a thiolated antibody was prepared by treating cetuximab with iminothiolane. The maleimide-functionalized SPIO nanoparticles were mixed with the thiolated antibody solution to form antibody-conjugated SPIO nanoparticles. The lipid-coated surface of SPIO nanoparticles provides a nonfouling property

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Journal of Nanobiotechnology

ISSN: 1477-3155

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