From: Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines
Pathogen-associated molecular pattern (PAMP) | Microorganism or classification | TLRs |
---|---|---|
Lipoproteins | Bacteria | TLR 1 |
Peptidoglycan and lipoteichoic acid | Gram positive bacteria | TLR 2 |
β-glucans | Fungi | |
dsRNA | Double-stranded and negative-stranded viruses | TLR 3 |
Lipopolysacharide (LPS) | Gram negative bacteria | TLR 4 |
Flagelin | Bacteria | TLR 5 |
Profilin | Toxoplasma gondii | |
Lipoproteins | Mycoplasma | TLR 6 |
Imidazoquinolines and ssRNA | Single-stranded viruses | TLR 7 and 8 |
Unmethylated CpG DNA motifs | Prokaryotic genomes and viral DNA | TLR 9 |