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Table 2 PAMPs recognized by specific CLRs

From: Liposomal vaccine formulations as prophylactic agents: design considerations for modern vaccines

Pathogen-associated molecular pattern (PAMP)

Microorganism or classification

CLRs

Mannan

Fungi

DC-SIGN

Man-LAM

M. tuberculosis

DC-SIGN and Dectin 2

LeX

Schistosoma mansonii and tissue ligands

DC-SIGN

LeY + LPS

Helicobacter pylori

LDNF (SP)

Fasciola hepatica

β-1,3-glucans

Fungi

Dectin 1

gp120

HIV-1

DC-SIGN

α-1,2-mannose

Fungi

Dectin 2

Glucosyl and mannosyl glycolipids

Malassezia pachydermatis and M. furfur

MINCLE

Mycobacterial cord factor

M. bovis BCG and M. tuberculosis

  1. Le X sialyl-Lewis X tetrasaccharide, Le Y Lewis Y tetrasaccharide, LPS lipopolysaccharide, LDNF fucosylated LacdiNAc