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Table 3 Limitations that hinder the broad use of omics technologies in nanotoxicology

From: Role of omics techniques in the toxicity testing of nanoparticles

Independent from the technology

Technology linked

Lack of standardization of particle exposure

Request for high sample quality (freezing, protection against degradation)

 Sample pre-treatment

Expertise in bioinformatics needed for data analysis

 Cell type used for testing

Lack of standardization of sample preparation

 Medium composition

Predictive value of the omics techniques not entirely clear

Relevant concentration range

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