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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Synergistic mechanism of Ag+–Zn2+ in anti-bacterial activity against Enterococcus faecalis and its application against dentin infection

Fig. 5

CCK-8 test on cytotoxicity of Ag+, Zn2+ and Ag+–Zn2+. a MC3T3-E1 cells (5 × 103 cells) exposed to different concentrations of AgNO3 (0.8 × 10−2, 1.6 × 10−2, 3.2 × 10−2, 6.4 × 10−2, 12.8 × 10−2, 25.6 × 10−2 and 51.2 × 10−2 mg/mL). b MC3T3-E1 cells (3 × 103 cells) exposed to different concentration of Zn(NO3)2·6H2O (5.6 × 10−2, 16.8 × 10−2, 33.6 × 10−2, 50.4 × 10−2 and 67.2 × 10−2 mg/L. c MC3T3-E1 cells (5 × 103) exposed to different atomic ratios of Ag+–Zn2+ (1:1, 1:3, 1:6, 1:9 and 1:12 with 3.2 × 10−2 mg/mL AgNO3). (BKG background, CHX chlorhexidine, BLK blank control group; Asterisk: significant difference when compared with the blank control group (p < 0.05); #significant difference compared with the 2% CHX group. p < 0.05)

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