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Fig. 5 | Journal of Nanobiotechnology

Fig. 5

From: Chitosan-DNA nanoparticles enhanced the immunogenicity of multivalent DNA vaccination on mice against Trueperella pyogenes infection

Fig. 5

Proliferation of T lymphocytes and changes of CD4+ and CD8+ T lymphocytes in spleens and the peripheral blood. The T lymphocytes from the spleen (a) and peripheral blood (b) of mice were separated and their proliferation was determined by MTT assay. The CD4+ and CD8+ T Lymphocytes were separated from the spleen (c) and peripheral blood (d) at the indicated time points and were sorted by flow cytometry. PBS was used as a control. Data represented mean ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001 (determined by one-way ANOVA followed by a Tukey–Kramer post hoc test)

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