Table 2 Gene regulation in AEII cells in response to CeO₂ and BaSO₄ after different exposure periods

Inflammatory cytokines and receptors

Ccl3

C–C motif chemokine ligand 3

Ccl17

C–C motif chemokine ligand 17

Cx3cr1

C–X3–C motif chemokine receptor 1

Il1α

Interleukin 1 alpha

Il1β

Interleukin 1 beta

Il1rn

Interleukin 1 receptor antagonist

Tnfsf4

Tumor necrosis factor superfamily member 4

Ccl2

C–C motif chemokine ligand 2

Ccl4

C–C motif chemokine ligand 4

Ccl7

C–C motif chemokine ligand 7

Ccl11

C–C motif chemokine ligand 11

Ccl20

C–C motif chemokine ligand 20

Ccl22

C–C motif chemokine ligand 22

Ccl24

C–C motif chemokine ligand 24

Pf4

platelet factor 4

Cxcl9

C–X–C motif chemokine ligand 9

Cd40lg

CD40 ligand

Il2rb

Interleukin 2 receptor, beta

Oxidative stress

Lpo

Lactoperoxidase

Noxo1

NADPH oxidase organizer 1

Hba1

Hemoglobin alpha, adult chain 2

Scd1

Stearoyl-Coenzyme A desaturase 1

Krt1

Keratin 1

DNA repair

Msh5

mutS homolog 5

Exo1

Exonuclease 1

Mutyh

MutY homolog (E. coli)

Apoptosis

Birc5

Baculoviral IAP repeat-containing 5

Lung cancer

Cyp1b1

Cytochrome P450, family 1, subfamily b, polypeptide 1

Fabp4

Fatty acid binding protein 4

Mmp12

Matrix metallopeptidase 12

Opcml

Opioid binding protein/cell adhesion molecule-like

Tcf21

Transcription factor 21

Thbs2

Thrombospondin 2

Top2a

Topoisomerase (DNA) II alpha

Total

34

11

18

24

9

10

15