Fig. 6
From: Multifunctionalized biocatalytic P22 nanoreactor for combinatory treatment of ER+ breast cancer
Effect of treatment with P22CYP and functionalized VLPs on MCF-7 cells sensitivity to tamoxifen by MTT assay. a Cell viability after an individual (EPT and PDT) and combinatory therapy where functionalized PpIX was activated by the irradiation of UV365 nm (3 J/cm2) and encapsulated CYP was activated by H2O2 (3 mM) treatment. b Effect of different concentrations of P22CYP-PpIX-PEG(EST) on cell viability in the absence and presence of UV irradiation and/or tamoxifen. Results are expressed as the mean ± SEM (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 using a two way ANOVA with Tukey post test