Table 4 The IC50 values of paclitaxel, curcumin alone and in combination on MCF-7 and MCF-10A cells, administered in the forms of free drug and drug niosomal form
Treatment type | IC50 values | |
|---|---|---|
On MCF-7 cells | On MCF-10A cells | |
Free curcumin solution | 44.60 ± 0.46 | 76.71 ± 0.45 |
Free paclitaxel solution | 13.54 ± 0.28 | 30.75 ± 0.22 |
Free paclitaxel + free curcumin solution | 8.36 ± 0.38 | 22.26 ± 0.48 |
Curcumin niosome | 14.90 ± 0.19 | 64.22 ± 0.36 |
Paclitaxel niosome | 3.73 ± 0.29 | 20.54 ± 0.49 |
Paclitaxel niosome + curcumin niosome | 1.57 ± 0.1 | 8.89 ± 0.46 |