From: Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release
Complexes | pH | K a (M−1) | ∆H (kcal/mol) | ∆G (kcal/mol) | − T∆S (kcal/mol) | n |
---|---|---|---|---|---|---|
KTN + PGM | 4.5 | (3.98 ± 1.82) × 105 | − 2.41 ± 0.02 | − 33.2 ± 0.13 | 30.8 ± 1.07 | 1.23 ± 0.02 |
KOS + PGM | 4.5 | (1.55 ± 0.71) × 104 | − 4.25 ± 0.05 | − 24.8 ± 0.20 | 20.6 ± 0.39 | 1.15 ± 0.03 |
KTN + PGM | 7.4 | (1.07 ± 0.12) × 104 | − 3.47 ± 0.10 | − 23.9 ± 0.16 | 20.4 ± 0.14 | 1.50 ± 0.01 |
KOS + PGM | 7.4 | (4.14 ± 1.15) × 103 | − 61.1 ± 1.53 | − 21.5 ± 1.01 | − 39.6 ± 1.13 | 1.27 ± 0.02 |