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Table 3 Thermodynamic parameters for binding of keratins to MUC at different pH

From: Development of keratin nanoparticles for controlled gastric mucoadhesion and drug release

Complexes pH K a (M−1) H (kcal/mol) G (kcal/mol) − TS (kcal/mol) n
KTN + PGM 4.5 (3.98 ± 1.82) × 105 − 2.41 ± 0.02 − 33.2 ± 0.13 30.8 ± 1.07 1.23 ± 0.02
KOS + PGM 4.5 (1.55 ± 0.71) × 104 − 4.25 ± 0.05 − 24.8 ± 0.20 20.6 ± 0.39 1.15 ± 0.03
KTN + PGM 7.4 (1.07 ± 0.12) × 104 − 3.47 ± 0.10 − 23.9 ± 0.16 20.4 ± 0.14 1.50 ± 0.01
KOS + PGM 7.4 (4.14 ± 1.15) × 103 − 61.1 ± 1.53 − 21.5 ± 1.01 − 39.6 ± 1.13 1.27 ± 0.02