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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: Nanoparticles engineered to bind cellular motors for efficient delivery

Fig. 2

Cellular distribution of NPs. a, d Mean fluorescence intensity (MFI) of intracellular Au@tiopronin modified with DynPro (Au@DynPro) or IntCt (Au@IntCt) after 1 h incubation with Vero cells (a) and other cell lines (d). Differences in MFI between Au@DBPs and Au@IntCt (control) were statistically significant p value of 0.001 (α = 0.05). In contrast, differences among Au@DBPs were not significant with a p value of 0.3 (α = 0.05; not shown). b Representative confocal images of Vero cells incubated with Au@DynPro or c Au@IntCt. eh Representative confocal images of SK-N-MC (e), HeLa (f), 293T (g) and MDCK cells incubated with Au@DynPro. Scale bar: 10 µm. i Time-dependent accumulation of Au@DynPro at several time points between 20 and 120 min, as indicated. j Fluorescence intensity percentages at increasing doses of Au@DynPro quantified by flow cytometry

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