Fig. 5
From: Nanoparticles engineered to bind cellular motors for efficient delivery
a, b Nuclear penetration capacity of Au@DynPro (n: nucleus). c–e Nuclear envelope appeared discontinuous as Au@DynPro shuttle the nucleus in Vero cells transfected with GFP-laminB receptor (c) and GFP-laminB1 (d, e) as shown in equatorial optical sections. Sample images show NPs entering the nucleus and nuclear lamina folding at sites of NPs entry. f Peptides shuttle the nucleus in Vero cells transfected with GFPB23 nucleolin (g) Au@DynPro in their way across the nucleus with visible imprints of their paths (b, arrow). Scale bar: 5 μm