Fig. 9From: Memantine loaded PLGA PEGylated nanoparticles for Alzheimer’s disease: in vitro and in vivo characterizationa Immunohistochemically (cortex) staining of amyloid plaques (green) and GFAP (red) of WT and APP/PS1 mice (untreated, MEM free and MEM loaded NPs). Bar reference equivalent to 100 µm. and b Amyloid plaques counting of APP/PS1 mice. Data represent mean ± SD; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001Back to article page