Fig. 6

Regression of cardiac hypertrophy in experiment rats. a, c Representative pictures of cardiac tissue cross-sections with haematoxylin/eosin (H/E) staining and Masson trichrome staining from different treatment groups (n = 8, each group, scale bar = 50 μm, magnification = ×400). b, d Quantitative analysis of average cross sectional area of myocytes (CSA) in cardiac tissues and cardiac collagen volume fraction (CVF). e Quantitative RT-PCR analysis of the hypertrophy-related genes β-MHC and fibrosis markers Collagen 1 and Collagen 3. GAPDH was used as an internal loading control. *p < 0.05 vs sham group; ^#p < 0.05 vs TAC group; ⁺p < 0.05 vs PCM-E2/PFPs + LIFU group