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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: Targeting extracellular vesicles to injured tissue using membrane cloaking and surface display

Fig. 4

Ischemic NRVM uptake assays of CDC-EV with Qdot 655 and ischemia targeting peptide cloaks. a Schematic of the design of Ischemic peptide and Qdot 655 membrane cloaks. b Example NanoSight particle tracking profile data for IschCDC-EV + Qdot 655 in visible and fluorescent modes. c FACS graphs of uptake rates of NRVM cells with CDC-EV labeled with Qdot 655−/+ ischemic targeting peptide (Isch) cloaks. Data are plotted as the average of raw Qdot 655 fluorescent readings for nonischemic (Ctrl) versus ischemic (Isch, H2O2-treated) NRVMs. n = 4 wells per experimental group

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