Fig. 5

Composition of the protein corona on PSNPs with a different surface chemistry determined with LC–MS/MS. The proteins were classified into seven groups according to their biological function using proteomics databases. a Distribution of the protein groups in DMEM⁺ and in the protein coronas of the PSNPs, expressed as a percentage of the total protein mass. b Number of protein molecules per particle clustered per protein group. c Top 20 proteins with the highest protein adsorption on the respective PSNP. Proteins are ordered alphabetically. The colour code indicates the protein group and the size of the spot represents the mass fraction (%), which is also given in numbers