Skip to main content

Table 2 Antibacterial activities of the tested formulations (MIC)

From: RETRACTED ARTICLE: Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis

Formulations MICa (µM)
Gram-positive Gram-negative
S. aureus ATCC29213 S. pneumoniae ATCC49619 A. pyogenes ATCC19411 E. coli ATCC25922 P. aeruginosa ATCC27853 S. typhimurium ATCC13311
BA solution 2 4 4 > 128 > 128 > 128
Nano-BAPLGA 1 2 2 16 32 32
Nano-BAF127 0.5 1 1 8 16 16
Nano-BAP123 0.5 1 1 4 8 4
Nano-BAP85 0.5 0.5 1 1 2 2
Polymyxin B > 128 > 128 > 128 1 1 2
  1. aMinimal inhibitory concentrations (MICs) were determined as the lowest concentration of the tested copolymers that inhibited bacterial growth