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Table 2 Antibacterial activities of the tested formulations (MIC)

From: RETRACTED ARTICLE: Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis

Formulations

MICa (µM)

Gram-positive

Gram-negative

S. aureus ATCC29213

S. pneumoniae ATCC49619

A. pyogenes ATCC19411

E. coli ATCC25922

P. aeruginosa ATCC27853

S. typhimurium ATCC13311

BA solution

2

4

4

> 128

> 128

> 128

Nano-BAPLGA

1

2

2

16

32

32

Nano-BAF127

0.5

1

1

8

16

16

Nano-BAP123

0.5

1

1

4

8

4

Nano-BAP85

0.5

0.5

1

1

2

2

Polymyxin B

> 128

> 128

> 128

1

1

2

  1. aMinimal inhibitory concentrations (MICs) were determined as the lowest concentration of the tested copolymers that inhibited bacterial growth