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Fig. 10 | Journal of Nanobiotechnology

Fig. 10

From: Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles

Fig. 10

Transfection of non-phagocytic cells, using mRNA:LPNs and mRNA:CS-PLGA at different ratios performed in epithelial A549 cells for 24 h and 48 h post-transfection using flow cytometer. mRNA complexed LPNs reveal a significant higher transgene expression over CS-PLGA NPs. Both NPs show higher transfection rates with higher mRNA:NP ratios and increasing transfection until 48 h post-transfection N = 4, mean ± SD (*p < 0.05 and **p  < 0.01)

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Journal of Nanobiotechnology

ISSN: 1477-3155

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