TY - JOUR AU - Meyer, S. C. AU - Levine, R. L. PY - 2014 DA - 2014// TI - Translational implications of somatic genomics in acute myeloid leukaemia JO - Lancet Oncol VL - 15 UR - https://doi.org/10.1016/S1470-2045(14)70008-7 DO - 10.1016/S1470-2045(14)70008-7 ID - Meyer2014 ER - TY - JOUR AU - Hoseini, S. S. AU - Cheung, N. K. PY - 2017 DA - 2017// TI - Acute myeloid leukemia targets for bispecific antibodies JO - Blood Cancer J VL - 7 UR - https://doi.org/10.1038/bcj.2017.2 DO - 10.1038/bcj.2017.2 ID - Hoseini2017 ER - TY - JOUR AU - Dohner, H. AU - Estey, E. AU - Grimwade, D. PY - 2017 DA - 2017// TI - Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel JO - Blood VL - 129 UR - https://doi.org/10.1182/blood-2016-08-733196 DO - 10.1182/blood-2016-08-733196 ID - Dohner2017 ER - TY - JOUR AU - Dohner, H. AU - Weisdorf, D. J. AU - Bloomfield, C. D. PY - 2015 DA - 2015// TI - Acute myeloid leukemia JO - N Engl J Med VL - 373 UR - https://doi.org/10.1056/NEJMra1406184 DO - 10.1056/NEJMra1406184 ID - Dohner2015 ER - TY - JOUR AU - McNerney, M. E. AU - Godley, L. A. AU - Beau, M. M. PY - 2017 DA - 2017// TI - Therapy-related myeloid neoplasms: when genetics and environment collide JO - Nat Rev Cancer VL - 17 UR - https://doi.org/10.1038/nrc.2017.60 DO - 10.1038/nrc.2017.60 ID - McNerney2017 ER - TY - JOUR AU - Fan, M. AU - Li, M. AU - Gao, L. PY - 2017 DA - 2017// TI - Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia JO - J Hematol Oncol VL - 10 UR - https://doi.org/10.1186/s13045-017-0519-7 DO - 10.1186/s13045-017-0519-7 ID - Fan2017 ER - TY - JOUR AU - Lim, S. H. AU - Dubielecka, P. M. AU - Raghunathan, V. M. PY - 2017 DA - 2017// TI - Molecular targeting in acute myeloid leukemia JO - J Transl Med VL - 15 UR - https://doi.org/10.1186/s12967-017-1281-x DO - 10.1186/s12967-017-1281-x ID - Lim2017 ER - TY - JOUR AU - Zhi, Y. AU - Li, B. AU - Yao, C. PY - 2018 DA - 2018// TI - Discovery of the selective and efficacious inhibitors of FLT3 mutations JO - Eur J Med Chem VL - 155 UR - https://doi.org/10.1016/j.ejmech.2018.06.010 DO - 10.1016/j.ejmech.2018.06.010 ID - Zhi2018 ER - TY - JOUR AU - Stein, E. M. PY - 2018 DA - 2018// TI - FLT3 inhibitors for relapsed or refractory acute myeloid leukaemia JO - Lancet Oncol VL - 19 UR - https://doi.org/10.1016/S1470-2045(18)30335-8 DO - 10.1016/S1470-2045(18)30335-8 ID - Stein2018 ER - TY - JOUR AU - Wang, R. AU - Li, Y. AU - Gong, P. AU - Gabrilove, J. AU - Waxman, S. AU - Jing, Y. PY - 2018 DA - 2018// TI - Arsenic trioxide and sorafenib induce synthetic lethality of FLT3-ITD acute myeloid leukemia cells JO - Mol Cancer Ther VL - 17 UR - https://doi.org/10.1158/1535-7163.MCT-17-0298 DO - 10.1158/1535-7163.MCT-17-0298 ID - Wang2018 ER - TY - JOUR AU - Battu, S. K. AU - Repka, M. A. AU - Maddineni, S. AU - Chittiboyina, A. G. AU - Avery, M. A. AU - Majumdar, S. PY - 2010 DA - 2010// TI - Physicochemical characterization of berberine chloride: a perspective in the development of a solution dosage form for oral delivery JO - AAPS PharmSciTech VL - 11 UR - https://doi.org/10.1208/s12249-010-9520-y DO - 10.1208/s12249-010-9520-y ID - Battu2010 ER - TY - JOUR AU - Yin, J. AU - Hou, Y. AU - Yin, Y. AU - Song, X. PY - 2017 DA - 2017// TI - Selenium-coated nanostructured lipid carriers used for oral delivery of berberine to accomplish a synergic hypoglycemic effect JO - Int J Nanomed VL - 12 UR - https://doi.org/10.2147/IJN.S144615 DO - 10.2147/IJN.S144615 ID - Yin2017 ER - TY - JOUR AU - Jabbarzadeh Kaboli, P. AU - Rahmat, A. AU - Ismail, P. AU - Ling, K. H. PY - 2014 DA - 2014// TI - Targets and mechanisms of berberine, a natural drug with potential to treat cancer with special focus on breast cancer JO - Eur J Pharmacol VL - 740 UR - https://doi.org/10.1016/j.ejphar.2014.06.025 DO - 10.1016/j.ejphar.2014.06.025 ID - Jabbarzadeh Kaboli2014 ER - TY - JOUR AU - Ortiz, L. M. AU - Lombardi, P. AU - Tillhon, M. AU - Scovassi, A. I. PY - 2014 DA - 2014// TI - Berberine, an epiphany against cancer JO - Molecules VL - 19 UR - https://doi.org/10.3390/molecules190812349 DO - 10.3390/molecules190812349 ID - Ortiz2014 ER - TY - JOUR AU - Wen, S. Q. AU - Jeyakkumar, P. AU - Avula, S. R. AU - Zhang, L. AU - Zhou, C. H. PY - 2016 DA - 2016// TI - Discovery of novel berberine imidazoles as safe antimicrobial agents by down regulating ROS generation JO - Bioorg Med Chem Lett VL - 26 UR - https://doi.org/10.1016/j.bmcl.2016.04.070 DO - 10.1016/j.bmcl.2016.04.070 ID - Wen2016 ER - TY - JOUR AU - Lee, C. H. AU - Chen, J. C. AU - Hsiang, C. Y. AU - Wu, S. L. AU - Wu, H. C. AU - Ho, T. Y. PY - 2007 DA - 2007// TI - Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells JO - Pharmacol Res VL - 56 UR - https://doi.org/10.1016/j.phrs.2007.06.003 DO - 10.1016/j.phrs.2007.06.003 ID - Lee2007 ER - TY - JOUR AU - Ahmed, T. AU - Gilani, A. U. AU - Abdollahi, M. AU - Daglia, M. AU - Nabavi, S. F. AU - Nabavi, S. M. PY - 2015 DA - 2015// TI - Berberine and neurodegeneration: a review of literature JO - Pharmacol Rep VL - 67 UR - https://doi.org/10.1016/j.pharep.2015.03.002 DO - 10.1016/j.pharep.2015.03.002 ID - Ahmed2015 ER - TY - JOUR AU - Ye, M. AU - Fu, S. AU - Pi, R. AU - He, F. PY - 2009 DA - 2009// TI - Neuropharmacological and pharmacokinetic properties of berberine: a review of recent research JO - J Pharm Pharmacol VL - 61 UR - https://doi.org/10.1211/jpp.61.07.0001 DO - 10.1211/jpp.61.07.0001 ID - Ye2009 ER - TY - JOUR AU - Abd El-Wahab, A. E. AU - Ghareeb, D. A. AU - Sarhan, E. E. AU - Abu-Serie, M. M. AU - Demellawy, M. A. PY - 2013 DA - 2013// TI - In vitro biological assessment of Berberis vulgaris and its active constituent, berberine: antioxidants, anti-acetylcholinesterase, anti-diabetic and anticancer effects JO - BMC Complement Altern Med VL - 13 UR - https://doi.org/10.1186/1472-6882-13-218 DO - 10.1186/1472-6882-13-218 ID - Abd El-Wahab2013 ER - TY - JOUR AU - Lin, C. C. AU - Kao, S. T. AU - Chen, G. W. AU - Ho, H. C. AU - Chung, J. G. PY - 2006 DA - 2006// TI - Apoptosis of human leukemia HL-60 cells and murine leukemia WEHI-3 cells induced by berberine through the activation of caspase-3 JO - Anticancer Res VL - 26 ID - Lin2006 ER - TY - JOUR AU - Lin, C. -. C. AU - Lin, S. -. Y. AU - Chung, J. -. G. AU - Lin, J. -. P. AU - Chen, G. -. W. AU - Kao, S. -. T. PY - 2006 DA - 2006// TI - Down-regulation of cyclin B1 and up-regulation of Wee1 by berberine promotes entry of leukemia cells into the G2/M-phase of the cell cycle JO - Anticancer Res VL - 26 ID - Lin2006 ER - TY - JOUR AU - Okubo, S. AU - Uto, T. AU - Goto, A. PY - 2017 DA - 2017// TI - Berberine induces apoptotic cell death via activation of caspase-3 and -8 in HL-60 human leukemia cells: nuclear localization and structure-activity relationships JO - Am J Chin Med VL - 45 UR - https://doi.org/10.1142/S0192415X17500811 DO - 10.1142/S0192415X17500811 ID - Okubo2017 ER - TY - JOUR AU - Mohammadi, S. AU - Seyedhoseini, F. S. AU - Asadi, J. AU - Yazdani, Y. PY - 2017 DA - 2017// TI - Effects of berberine on the secretion of cytokines and expression of genes involved in cell cycle regulation in THP-1 monocytic cell line JO - Iran J Basic Med Sci VL - 20 ID - Mohammadi2017 ER - TY - JOUR AU - Li, P. AU - Diab, S. AU - Yu, M. PY - 2016 DA - 2016// TI - Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells JO - Oncotarget VL - 7 ID - Li2016 ER - TY - JOUR AU - Tan, W. AU - Li, Y. AU - Chen, M. AU - Wang, Y. PY - 2011 DA - 2011// TI - Berberine hydrochloride: anticancer activity and nanoparticulate delivery system JO - Int J Nanomed VL - 6 UR - https://doi.org/10.2147/IJN.S22683 DO - 10.2147/IJN.S22683 ID - Tan2011 ER - TY - JOUR AU - Xiong, W. AU - Sang, W. AU - Linghu, K. G. PY - 2018 DA - 2018// TI - Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine JO - Int J Nanomed VL - 13 UR - https://doi.org/10.2147/IJN.S163763 DO - 10.2147/IJN.S163763 ID - Xiong2018 ER - TY - JOUR AU - Li, Y. J. AU - Hu, X. B. AU - Lu, X. L. PY - 2017 DA - 2017// TI - Nanoemulsion-based delivery system for enhanced oral bioavailability and caco-2 cell monolayers permeability of berberine hydrochloride JO - Drug Deliv VL - 24 UR - https://doi.org/10.1080/10717544.2017.1410257 DO - 10.1080/10717544.2017.1410257 ID - Li2017 ER - TY - JOUR AU - Najar, I. A. AU - Sachin, B. S. AU - Sharma, S. C. AU - Satti, N. K. AU - Suri, K. A. AU - Johri, R. K. PY - 2010 DA - 2010// TI - Modulation of P-glycoprotein ATPase activity by some phytoconstituents JO - Phytother Res VL - 24 UR - https://doi.org/10.1002/ptr.2951 DO - 10.1002/ptr.2951 ID - Najar2010 ER - TY - JOUR AU - Qiu, W. AU - Jiang, X. H. AU - Liu, C. X. AU - Ju, Y. AU - Jin, J. X. PY - 2009 DA - 2009// TI - Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp JO - Phytother Res VL - 23 UR - https://doi.org/10.1002/ptr.2808 DO - 10.1002/ptr.2808 ID - Qiu2009 ER - TY - JOUR AU - Zhang, Z. AU - Qian, H. AU - Yang, M. PY - 2017 DA - 2017// TI - Gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment JO - Int J Nanomed VL - 12 UR - https://doi.org/10.2147/IJN.S127256 DO - 10.2147/IJN.S127256 ID - Zhang2017 ER - TY - JOUR AU - Onodera, T. AU - Kuriyama, I. AU - Andoh, T. PY - 2015 DA - 2015// TI - Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion JO - Int J Mol Med VL - 35 UR - https://doi.org/10.3892/ijmm.2015.2186 DO - 10.3892/ijmm.2015.2186 ID - Onodera2015 ER - TY - JOUR AU - Ahmad, G. AU - Sadda, R. AU - Botchkina, G. AU - Ojima, I. AU - Egan, J. AU - Amiji, M. PY - 2017 DA - 2017// TI - Nanoemulsion formulation of a novel taxoid DHA-SBT-1214 inhibits prostate cancer stem cell-induced tumor growth JO - Cancer Lett VL - 406 UR - https://doi.org/10.1016/j.canlet.2017.08.004 DO - 10.1016/j.canlet.2017.08.004 ID - Ahmad2017 ER - TY - JOUR AU - Li, Y. F. AU - Sun, H. W. AU - Gao, R. PY - 2015 DA - 2015// TI - Inhibited biofilm formation and improved antibacterial activity of a novel nanoemulsion against cariogenic Streptococcus mutans in vitro and in vivo JO - Int J Nanomed VL - 10 UR - https://doi.org/10.2217/nnm.14.179 DO - 10.2217/nnm.14.179 ID - Li2015 ER - TY - JOUR AU - Sun, H. AU - Wei, C. AU - Liu, B. PY - 2015 DA - 2015// TI - Induction of systemic and mucosal immunity against methicillin-resistant Staphylococcus aureus infection by a novel nanoemulsion adjuvant vaccine JO - Int J Nanomed VL - 10 UR - https://doi.org/10.2147/IJN.S91529 DO - 10.2147/IJN.S91529 ID - Sun2015 ER - TY - JOUR AU - Cai, W. AU - Deng, W. AU - Yang, H. AU - Chen, X. AU - Jin, F. PY - 2012 DA - 2012// TI - A propofol microemulsion with low free propofol in the aqueous phase: formulation, physicochemical characterization, stability and pharmacokinetics JO - Int J Pharm VL - 436 UR - https://doi.org/10.1016/j.ijpharm.2012.07.008 DO - 10.1016/j.ijpharm.2012.07.008 ID - Cai2012 ER - TY - JOUR AU - Sahibzada, M. U. K. AU - Sadiq, A. AU - Faidah, H. S. PY - 2018 DA - 2018// TI - Berberine nanoparticles with enhanced in vitro bioavailability: characterization and antimicrobial activity JO - Drug Des Dev Ther VL - 12 UR - https://doi.org/10.2147/DDDT.S156123 DO - 10.2147/DDDT.S156123 ID - Sahibzada2018 ER - TY - JOUR AU - Myc, A. AU - Kukowska-Latallo, J. F. AU - Bielinska, A. U. PY - 2003 DA - 2003// TI - Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsion JO - Vaccine VL - 21 UR - https://doi.org/10.1016/S0264-410X(03)00381-5 DO - 10.1016/S0264-410X(03)00381-5 ID - Myc2003 ER - TY - JOUR AU - Feng, R. AU - Zhao, Z. X. AU - Ma, S. R. AU - Guo, F. AU - Wang, Y. AU - Jiang, J. D. PY - 2018 DA - 2018// TI - Gut microbiota-regulated pharmacokinetics of berberine and active metabolites in beagle dogs after oral administration JO - Front Pharmacol VL - 9 UR - https://doi.org/10.3389/fphar.2018.00214 DO - 10.3389/fphar.2018.00214 ID - Feng2018 ER - TY - JOUR AU - Ranganathan, P. AU - Yu, X. AU - Na, C. PY - 2012 DA - 2012// TI - Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia JO - Blood VL - 120 UR - https://doi.org/10.1182/blood-2012-04-423160 DO - 10.1182/blood-2012-04-423160 ID - Ranganathan2012 ER - TY - JOUR AU - Ranganathan, P. AU - Kashyap, T. AU - Yu, X. PY - 2016 DA - 2016// TI - XPO1 inhibition using selinexor synergizes with chemotherapy in acute myeloid leukemia by targeting DNA repair and restoring topoisomerase IIalpha to the nucleus JO - Clin Cancer Res VL - 22 UR - https://doi.org/10.1158/1078-0432.CCR-15-2885 DO - 10.1158/1078-0432.CCR-15-2885 ID - Ranganathan2016 ER - TY - JOUR AU - Wang, Y. AU - Zhi, Y. AU - Jin, Q. PY - 2018 DA - 2018// TI - Discovery of 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)p henyl)-1H-pyrazole-3-carboxamide (FN-1501), an FLT3- and CDK-kinase inhibitor with potentially high efficiency against acute myelocytic leukemia JO - J Med Chem VL - 61 UR - https://doi.org/10.1021/acs.jmedchem.7b01261 DO - 10.1021/acs.jmedchem.7b01261 ID - Wang2018 ER - TY - JOUR AU - Bachas, C. AU - Schuurhuis, G. J. AU - Zwaan, C. M. PY - 2015 DA - 2015// TI - Gene expression profiles associated with pediatric relapsed AML JO - PLoS ONE VL - 10 UR - https://doi.org/10.1371/journal.pone.0121730 DO - 10.1371/journal.pone.0121730 ID - Bachas2015 ER - TY - JOUR AU - Kiyoi, H. AU - Yanada, M. AU - Ozekia, K. PY - 2005 DA - 2005// TI - Clinical significance of FLT3 in leukemia JO - Int J Hematol VL - 82 UR - https://doi.org/10.1532/IJH97.05066 DO - 10.1532/IJH97.05066 ID - Kiyoi2005 ER - TY - JOUR AU - Thiede, C. AU - Steudel, C. AU - Mohr, B. PY - 2002 DA - 2002// TI - Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis JO - Blood VL - 99 UR - https://doi.org/10.1182/blood.V99.12.4326 DO - 10.1182/blood.V99.12.4326 ID - Thiede2002 ER - TY - JOUR AU - Ravandi, F. AU - Kantarjian, H. AU - Faderl, S. PY - 2010 DA - 2010// TI - Outcome of patients with FLT3-mutated acute myeloid leukemia in first relapse JO - Leuk Res VL - 34 UR - https://doi.org/10.1016/j.leukres.2009.10.001 DO - 10.1016/j.leukres.2009.10.001 ID - Ravandi2010 ER - TY - JOUR AU - Wang, S. AU - Yu, J. AU - Suvira, M. AU - Setlow, P. AU - Li, Y. Q. PY - 2015 DA - 2015// TI - Uptake of and resistance to the antibiotic berberine by individual dormant, germinating and outgrowing Bacillus spores as monitored by laser tweezers Raman spectroscopy JO - PLoS ONE VL - 10 UR - https://doi.org/10.1371/journal.pone.0144183 DO - 10.1371/journal.pone.0144183 ID - Wang2015 ER - TY - JOUR AU - La, X. AU - Zhang, L. AU - Li, Z. AU - Yang, P. AU - Wang, Y. PY - 2017 DA - 2017// TI - Berberine-induced autophagic cell death by elevating GRP78 levels in cancer cells JO - Oncotarget VL - 8 UR - https://doi.org/10.18632/oncotarget.14959 DO - 10.18632/oncotarget.14959 ID - La2017 ER - TY - JOUR AU - Shen, R. AU - Kim, J. J. AU - Yao, M. AU - Elbayoumi, T. A. PY - 2016 DA - 2016// TI - Development and evaluation of vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate-mixed polymeric phospholipid micelles of berberine as an anticancer nanopharmaceutical JO - Int J Nanomed VL - 11 ID - Shen2016 ER - TY - JOUR AU - Hak, S. AU - Garaiova, Z. AU - Olsen, L. T. AU - Nilsen, A. M. AU - Lange, D. a. v. i. e. s. C. PY - 2015 DA - 2015// TI - The effects of oil-in-water nanoemulsion polyethylene glycol surface density on intracellular stability, pharmacokinetics, and biodistribution in tumor bearing mice JO - Pharm Res VL - 32 UR - https://doi.org/10.1007/s11095-014-1553-6 DO - 10.1007/s11095-014-1553-6 ID - Hak2015 ER - TY - JOUR AU - Winter, E. AU - Pizzol, C. D. AU - Locatelli, C. PY - 2014 DA - 2014// TI - In vitro and in vivo effects of free and chalcones-loaded nanoemulsions: insights and challenges in targeted cancer chemotherapies JO - Int J Environ Res Public Health VL - 11 UR - https://doi.org/10.3390/ijerph111010016 DO - 10.3390/ijerph111010016 ID - Winter2014 ER - TY - JOUR AU - Wang, Z. AU - Wu, J. AU - Zhou, Q. AU - Wang, Y. AU - Chen, T. PY - 2015 DA - 2015// TI - Berberine nanosuspension enhances hypoglycemic efficacy on streptozotocin induced diabetic C57BL/6 mice JO - Evid Based Complement Alternat Med VL - 2015 ID - Wang2015 ER - TY - JOUR AU - Chen, L. AU - Lu, X. AU - Liang, X. PY - 2016 DA - 2016// TI - Mechanistic studies of the transport of peimine in the Caco-2 cell model JO - Acta Pharm Sin B VL - 6 UR - https://doi.org/10.1016/j.apsb.2016.01.006 DO - 10.1016/j.apsb.2016.01.006 ID - Chen2016 ER - TY - JOUR AU - Planas, J. M. AU - Alfaras, I. AU - Colom, H. AU - Juan, M. E. PY - 2012 DA - 2012// TI - The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters JO - Arch Biochem Biophys VL - 527 UR - https://doi.org/10.1016/j.abb.2012.06.004 DO - 10.1016/j.abb.2012.06.004 ID - Planas2012 ER - TY - JOUR AU - Gopalakrishnapillai, A. AU - Kolb, E. A. AU - McCahan, S. M. AU - Barwe, S. P. PY - 2017 DA - 2017// TI - Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia JO - Leuk Res VL - 58 UR - https://doi.org/10.1016/j.leukres.2017.05.004 DO - 10.1016/j.leukres.2017.05.004 ID - Gopalakrishnapillai2017 ER - TY - JOUR AU - Lopes de Menezes, D. E. AU - Peng, J. AU - Garrett, E. N. PY - 2005 DA - 2005// TI - CHIR-258: a potent inhibitor of FLT3 kinase in experimental tumor xenograft models of human acute myelogenous leukemia JO - Clin Cancer Res VL - 11 UR - https://doi.org/10.1158/1078-0432.CCR-05-0358 DO - 10.1158/1078-0432.CCR-05-0358 ID - Lopes de Menezes2005 ER - TY - JOUR AU - Yu, F. S. AU - Yang, J. S. AU - Lin, H. J. PY - 2007 DA - 2007// TI - Berberine inhibits WEHI-3 leukemia cells in vivo JO - In Vivo VL - 21 ID - Yu2007 ER -