Orally administered gold nanoparticles protect against colitis by attenuating Toll-like receptor 4- and reactive oxygen/nitrogen species-mediated inflammatory responses but could induce gut dysbiosis in mice

Table 2 The accumulation of gold in the kidney after oral administration of AuNPs in mice

AuNPs	Approximate doses (μg/kg body weight/day)	Au contents in kidney (pg/g wet weight)¹
Au-5 nm/PVP	25	158.6 ± 27.9^c
Au-5 nm/Citrate	25	128.9 ± 15.6^d
Au-5 nm/TA	25	119.5 ± 19.1^d
Au-10 nm/TA	22	143.5 ± 16.9^cd
Au-15 nm/TA	20	265.2 ± 28.6^a
Au-30 nm/TA	18	239.3 ± 19.8^b
Au-60 nm/TA	15	121.3 ± 28.3^d

¹Values are means ± standard deviations. Means in a column without a common superscript letter (a, b, c and d) are statistically different (ANOVA followed by LSD test, P < 0.05)

ISSN: 1477-3155