Fig. 4
From: Biosynthesis of flower-shaped Au nanoclusters with EGCG and their application for drug delivery
A Distribution and tumor accumulation of Cy 5.5-nanoparticles in HeLa tumor-bearing mice receiving intravenous injection of the indicated formulations. B Ex vivo fluorescence imaging of the tumor and normal tissues harvested from the euthanized HeLa tumor-bearing nude mice. The images were taken 24 h after the injection. H, Li, Lu, K, S, and T represent heart, liver, lung, kidney, spleen, and tumor, respectively. C Cy 5.5 fluorescence intensity in tumor tissues collected at 24 h following systemic injection. P < 0.05. (a) DOX-Cy 5.5, (b) MTX-Cy 5.5, (c) Au-Cys-Cy 5.5 NCs, (d) Au-Cys-MTX/DOX-Cy 5.5 NCs