Fig. 8

HA-eNPs/ATRA enhanced the inhibition of tumor growth in the in situ lung metastasis tumor-bearing mice. a Images of the B16F10-bearing lungs on day 24 after five consecutive i.v. injections of NP formulations (n = 5). b Antitumor effects of various treatments evaluated according to B16F10-bearing lung weight (n = 5). c Histological staining of the B16F10-bearing lungs after various treatments (arrows indicate tumor nodules, n = 5)